Located 2.2 km from La Flora Ecological Park, the smoke-free Hotel Mi Palermo Bucaramanga is approximately a 5-minute walk from the Parque Santander. Offering 24-hour reception and wake-up calls, this 2-star hotel also features Wi-Fi in public areas.

The hotel is about 5 km from Palonegro International airport and in the vicinity of such cultural venues as the Centro Cultural del Oriente. The Mi Palermo Bucaramanga is a mere 1.3 km from the Parque de los Niños and 700 metres from the Bolivar Park. The San Francisco Park is within 20 minutes' walk of the property. Estacion Metrolinea San Mateo bus station can be found right near this Bucaramanga hotel.

The accommodation is within a 200-metre distance of the restaurant Entre Panes.